Nucleofill SOFT+ CE (EYES)
Nucleofill SOFT+ CE (EYES) is a specialised polynucleotide formulation developed for the delicate periocular area. Supplied as a 2ml pre-filled syringe, it is positioned for professional skin-quality improvement around the eyes, including the appearance of fine lines, wrinkles and dark circles.
Nucleofill SOFT+ CE (EYES) Overview
Nucleofill SOFT+ CE (EYES) is a dedicated polynucleotide skin booster designed for the delicate area surrounding the eyes. Unlike traditional dermal fillers that primarily focus on adding structural volume, this formulation is positioned around skin quality, hydration, tissue redensification and the visible appearance of fine lines and dark circles.
Product documentation identifies the Soft Plus formulation with 15mg of polynucleotides in 2ml, corresponding to approximately 0.75%. The same technical material lists a molecular weight of approximately 50–100 kDa and positions the Soft Plus formulation for concerns including wrinkles and dark circles. :contentReference[oaicite:0]{index=0}
The product is marketed under names including Nucleofill Soft Plus Eyes and Nucleofill Eyes, with current professional suppliers using the name Nucleofill SOFT+ CE (EYES). Current listings describe it as a professional periocular polynucleotide treatment supplied in a 2ml syringe. :contentReference[oaicite:1]{index=1}
Why Choose Nucleofill SOFT+ CE (EYES)?
The periocular area requires product selection that reflects the characteristics of thin, delicate skin. Nucleofill SOFT+ CE (EYES) is specifically positioned for the eye contour rather than as a general facial volumising filler.
Its low-molecular-weight polynucleotide formulation is intended to support professional skin-rejuvenation strategies focused on tissue quality. Manufacturer-related documentation describes the Soft Plus formulation as containing low-molecular-weight polynucleotide fragments in the approximately 50–100 kDa range. :contentReference[oaicite:2]{index=2}
This makes Nucleofill SOFT+ CE (EYES) a distinct option for clinics that want a dedicated polynucleotide product within their under-eye skin-booster portfolio.
Key Features of Nucleofill SOFT+ CE (EYES)
Dedicated Eye Formula
Developed specifically for the periocular area, where thin and delicate skin requires specialised product positioning.
15mg Polynucleotides
Technical product information identifies the Soft Plus formulation as containing 15mg of polynucleotides in a 2ml presentation. :contentReference[oaicite:3]{index=3}
2ml Presentation
The product is supplied as a 2ml pre-filled syringe according to current professional supplier listings. :contentReference[oaicite:4]{index=4}
Low-Molecular-Weight PN
The Soft Plus technical description identifies polynucleotide fragments with an approximate molecular-weight range of 50–100 kDa. :contentReference[oaicite:5]{index=5}
Skin-Quality Focus
The product is positioned for visible skin-quality concerns such as fine lines, wrinkles, dark circles and reduced periocular skin quality.
Professional Product
Current European supplier listings position Nucleofill SOFT+ CE (EYES) for professional aesthetic use. :contentReference[oaicite:6]{index=6}
Nucleofill SOFT+ CE (EYES) for the Periocular Area
The skin surrounding the eyes is one of the most delicate areas of the face and commonly displays visible signs of ageing earlier than thicker facial skin. Nucleofill SOFT+ CE (EYES) was developed specifically around this requirement rather than being a general-purpose polynucleotide formula.
Product documentation lists the periocular area as the primary treatment region and identifies concerns including dark circles, periocular wrinkles, dermoepidermal tissue redensification and superficial wrinkles without the use of traditional volumising fillers. :contentReference[oaicite:7]{index=7}
Professional product descriptions also position Nucleofill Eyes around hydration, skin quality and visible rejuvenation of the under-eye area. :contentReference[oaicite:8]{index=8}
Polynucleotide Technology and Skin Quality
Polynucleotides are DNA-derived nucleotide chains used in professional aesthetic formulations focused on skin quality and regenerative support. Nucleofill’s Soft Plus formulation uses purified polynucleotide material and is differentiated from more concentrated Nucleofill formulations by its lower concentration and low-molecular-weight profile.
The current Nucleofill technical brochure identifies Soft Plus at 0.75%, with 15mg PDRN/polynucleotide content in a 2ml syringe and an approximate molecular weight of 50–100 kDa. Its stated cosmetic-aesthetic positioning includes improvement of wrinkles, dark circles and circulation-related skin appearance. :contentReference[oaicite:9]{index=9}
This formulation profile is particularly relevant when a clinic wants to separate its eye-area polynucleotide offering from stronger or more concentrated products intended for broader facial or body applications.
Professional Applications
Fine Lines
Designed for professional management of the appearance of fine periocular lines and superficial wrinkles.
Dark Circles
Nucleofill Soft Plus documentation specifically identifies dark circles among its periocular indications. :contentReference[oaicite:10]{index=10}
Skin Redensification
Positioned for improvement of periocular skin quality and dermoepidermal tissue redensification.
Eye-Contour Rejuvenation
A dedicated option for clinics providing professional polynucleotide-based eye-contour rejuvenation.
Nucleofill SOFT+ CE (EYES) vs Other Nucleofill Formulations
| Characteristic | SOFT+ CE (EYES) | Nucleofill Strong | Nucleofill Medium Plus |
|---|---|---|---|
| Primary Positioning | Periocular / eye area | Broader facial rejuvenation | Hair/scalp-focused positioning |
| PN/PDRN Content | 15mg / 2ml | 37.5mg / 1.5ml | 40mg / 2ml |
| Concentration | 0.75% | 2.5% | 2.0% |
| Molecular Weight | Approximately 50–100 kDa | Approximately 2,500 kDa | Approximately 1,500 kDa |
| Pack | 1 × 2ml syringe | 1 × 1.5ml syringe | 1 × 2ml syringe |
Comparative specifications are based on the Nucleofill technical brochure. Product versions and market-specific packaging should be verified against the supplied product documentation. :contentReference[oaicite:11]{index=11}
Nucleofill SOFT+ CE (EYES) Specifications
| Brand | Nucleofill |
| Product | Nucleofill SOFT+ CE (EYES) |
| Manufacturer | Promoitalia Medical Aesthetics |
| Product Type | Polynucleotide skin booster / biostimulator |
| Volume | 2ml |
| Polynucleotide Content | 15mg / 2ml |
| Concentration | 0.75% |
| Molecular Weight | Approximately 50–100 kDa |
| pH | 6.8–7.2 |
| Viscosity | Approximately 28–35 Pa·s in technical documentation |
| Needles | 2 × 30G needles listed with the product in current technical/supplier documentation |
| Primary Area | Periocular / eye area |
Professional Nucleofill Eye Booster for Clinics
Nucleofill SOFT+ CE (EYES) gives professional aesthetic clinics a dedicated product for the periocular segment of their polynucleotide portfolio. Its 2ml presentation and eye-specific positioning make it distinct from broader Nucleofill formulations.
For clinics stocking multiple skin boosters, separating products according to formulation, concentration and intended treatment area helps maintain clear inventory management. Nucleofill Soft Plus is specifically positioned around the eye contour, while other Nucleofill products have different concentrations and target areas. :contentReference[oaicite:12]{index=12}
This product should be used only by appropriately trained professionals and strictly according to the current manufacturer instructions for use, applicable local regulations and supplied packaging.
Shop Professional Nucleofill Products
Explore Nucleofill SOFT+ CE (EYES) and other professional aesthetic skin boosters available from Pro Aesthetic Hub Europe.
Nucleofill SOFT+ CE (EYES) Product Information
Nucleofill product documentation identifies Soft Plus as the lower-concentration Nucleofill formulation specifically associated with the periocular area, with 15mg of polynucleotide in 2ml, 0.75% concentration and approximately 50–100 kDa molecular weight. :contentReference[oaicite:13]{index=13}
For additional product information, the current Nucleofill product page for Soft Plus Eyes can be viewed here:
Nucleofill Soft Plus Eyes
.
Current professional supplier information also lists the product as
Nucleofill SOFT+ CE (EYES)
and confirms the 2ml syringe presentation. :contentReference[oaicite:14]{index=14}
Frequently Asked Questions
What is Nucleofill SOFT+ CE (EYES)?
Nucleofill SOFT+ CE (EYES) is a professional polynucleotide skin booster specifically positioned for the delicate periocular area. It is supplied in a 2ml presentation and is designed around concerns such as fine lines, wrinkles, dark circles and skin-quality improvement.
How much polynucleotide does Nucleofill SOFT+ CE (EYES) contain?
Technical Nucleofill documentation identifies Soft Plus as containing 15mg of polynucleotide in 2ml, equivalent to approximately 0.75%. :contentReference[oaicite:15]{index=15}
What area is Nucleofill SOFT+ CE (EYES) designed for?
It is specifically positioned for the periocular or eye area. Product documentation identifies concerns including dark circles, periocular wrinkles and skin redensification around the eyes. :contentReference[oaicite:16]{index=16}
Is Nucleofill SOFT+ CE (EYES) a dermal filler?
No. It is positioned as a polynucleotide skin booster/biostimulator rather than a conventional volumising hyaluronic-acid dermal filler. Its focus is skin quality and periocular rejuvenation rather than structural volume replacement.
How much product is supplied?
The product is supplied as one 2ml syringe. Current professional supplier listings confirm the 2ml presentation. :contentReference[oaicite:17]{index=17}
Does the package include needles?
Technical and supplier documentation lists two 30G needles with the 2ml Soft Plus presentation. Exact needle dimensions can vary between documentation versions, so the supplied packaging and current IFU should be treated as the final reference. :contentReference[oaicite:18]{index=18}
Is Nucleofill SOFT+ CE (EYES) for professional use?
Yes. Current European supplier listings position Nucleofill SOFT+ CE (EYES) for professional aesthetic use. It should only be used by appropriately trained and qualified practitioners in accordance with the current product documentation and applicable local requirements. :contentReference[oaicite:19]{index=19}
Order Nucleofill SOFT+ CE (EYES)
Add Nucleofill SOFT+ CE (EYES) to your professional skin-booster portfolio for dedicated periocular polynucleotide applications.
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